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Duodenectomy is a surgical procedure that involves the removal of part or all of the duodenum, the first section of the small intestine that connects to the stomach. This procedure is typically performed to treat conditions affecting the duodenum, such as duodenal cancer, severe duodenal ulcers, or benign tumors. It may also be indicated for complex cases of Crohn's disease or other severe inflammatory conditions affecting this part of the digestive tract. The procedure can be performed through open surgery with a large abdominal incision or using laparoscopic techniques, which involve smaller incisions and specialized instruments. The extent of the duodenectomy depends on the underlying condition. In some cases, only a portion of the duodenum is removed, while in more severe cases, the entire duodenum may be excised. After removal, the remaining sections of the digestive tract are usually reconnected to restore continuity. Complications of duodenectomy can include infection, bleeding, and leakage at the site where the digestive tract is reconnected. There is also a risk of bowel obstruction, as well as injury to surrounding organs such as the pancreas or liver. Postoperative issues may involve digestive problems, such as changes in bowel habits, difficulty with nutrient absorption, or abdominal pain. Additionally, patients may experience changes in their nutritional status and require dietary adjustments or supplementation. Despite these risks, duodenectomy can be an effective treatment for severe duodenal conditions, improving symptoms and overall quality of life.